演讲嘉宾-Lucia Gemma Delogu

Lucia Gemma Delogu
University of Sassari
Dr. Lucia Gemma Delogu served the University of Sassari, Italy, as Assistant Professor of Biochemistry (2012-2017). She has worked at the University of Southern California, Los Angeles (2007-2009), as visiting researcher at the Sanford-Burnham Institute of San Diego, CA, USA in 2008 and at the Department of Health and Human Services at the NIH in Bethesda, MD in 2013. Dr. Delogu has been appointed as Senior Visiting Professor under the “Program Excellence in Science” at Technische Universitat Dresden, Germany (2016, 2017). In 2011, she was selected as one of the “200 Best Young Talents of Italy” from the Italian Ministry of Youth (Rome, Italy). She has received several awards including the Marie S. Curie Individual Fellow under Horizon 2020 by the European Commission, the “Medicine, Biology e Nanotechnology Award” in 2012 from the Association of GianFranco Del Prete and the “Bedside to bench & Back Lecture Series Achievement Award” from the National Institute of Health, Bethesda, USA (2013). She served the European Commission as invited expert for review panels of FP7 FET Flagships. Beyond different National Grants (i.e. PRIN-MIUR, AIL.), she has been the Scientific  Coordinator of two interdisciplinary European Projects on Nanomedicine involving 10 leading Institutions in EU and extra EU Countries including China, USA and Qatar. Dr. Delogu has been Project researcher at the University of Trieste and in 2018 joined the IRP where she is currently leading the ImmuneNano-lab.
演讲题目:Graphene interactions with human immune blood cells.
主题会场石墨烯在临床医疗领域的应用
开始时间
结束时间
内容摘要

“Despite significant progress of nanotechnology also in medicine, the development of new nanomaterials able to treat and prevents diseases such as cancer is still one of the biggest challenges. A critical step is represented by the assessment of nanomaterial impact on the complexity of the immune system. Graphene oxide, has attracted tremendous interest being explored for many potential applications in medicine. To clarify its action on the immune cells, we proposed an integrative analytical pipeline encompassing genomic and cellular characterization of the impact of graphene on primary immune cells. We used whole-transcriptomic analysis  for functional and molecular characterization. We then employed single cell mass cytometry which can analyze up to 40 markers at the same time. We found that only the functionalized GONH2 was able to induce a specific dendritic cell and monocyte activation skewed toward a Th1/M1 response, as demonstrated by the increased production of classic M1 cytokines (TNFα, IL6, and CCL4). Our findings report a new pipeline able to carefully analyse the immunological impact of new nanoscale platforms including graphene for a successful application in medicine.”

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联系我们
400-110-3655   

E-mail: meeting@c-gia.cn   meeting01@c-gia.cn

参展电话:13646399362(苏老师)

主讲申请:19991951101(王老师)

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凯发_Lucia Gemma Delogu

凯发

演讲嘉宾-Lucia Gemma Delogu

Lucia Gemma Delogu
University of Sassari
Dr. Lucia Gemma Delogu served the University of Sassari, Italy, as Assistant Professor of Biochemistry (2012-2017). She has worked at the University of Southern California, Los Angeles (2007-2009), as visiting researcher at the Sanford-Burnham Institute of San Diego, CA, USA in 2008 and at the Department of Health and Human Services at the NIH in Bethesda, MD in 2013. Dr. Delogu has been appointed as Senior Visiting Professor under the “Program Excellence in Science” at Technische Universitat Dresden, Germany (2016, 2017). In 2011, she was selected as one of the “200 Best Young Talents of Italy” from the Italian Ministry of Youth (Rome, Italy). She has received several awards including the Marie S. Curie Individual Fellow under Horizon 2020 by the European Commission, the “Medicine, Biology e Nanotechnology Award” in 2012 from the Association of GianFranco Del Prete and the “Bedside to bench & Back Lecture Series Achievement Award” from the National Institute of Health, Bethesda, USA (2013). She served the European Commission as invited expert for review panels of FP7 FET Flagships. Beyond different National Grants (i.e. PRIN-MIUR, AIL.), she has been the Scientific  Coordinator of two interdisciplinary European Projects on Nanomedicine involving 10 leading Institutions in EU and extra EU Countries including China, USA and Qatar. Dr. Delogu has been Project researcher at the University of Trieste and in 2018 joined the IRP where she is currently leading the ImmuneNano-lab.
演讲题目:Graphene interactions with human immune blood cells.
主题会场石墨烯在临床医疗领域的应用
开始时间
结束时间
内容摘要

“Despite significant progress of nanotechnology also in medicine, the development of new nanomaterials able to treat and prevents diseases such as cancer is still one of the biggest challenges. A critical step is represented by the assessment of nanomaterial impact on the complexity of the immune system. Graphene oxide, has attracted tremendous interest being explored for many potential applications in medicine. To clarify its action on the immune cells, we proposed an integrative analytical pipeline encompassing genomic and cellular characterization of the impact of graphene on primary immune cells. We used whole-transcriptomic analysis  for functional and molecular characterization. We then employed single cell mass cytometry which can analyze up to 40 markers at the same time. We found that only the functionalized GONH2 was able to induce a specific dendritic cell and monocyte activation skewed toward a Th1/M1 response, as demonstrated by the increased production of classic M1 cytokines (TNFα, IL6, and CCL4). Our findings report a new pipeline able to carefully analyse the immunological impact of new nanoscale platforms including graphene for a successful application in medicine.”

关于主办方

联系我们
400-110-3655   

E-mail: meeting@c-gia.cn   meeting01@c-gia.cn

参展电话:13646399362(苏老师)

主讲申请:19991951101(王老师)

官方微信订阅号
Copyright © 中国国际石墨烯创新大会 版权所有     运营机构:北京现代华清材料科技发展有限责任公司
grapchina.org 京ICP备10026874号-12   grapchina.cn 京ICP备10026874号-23
京公网安备 11010802023402号
分享到: